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LOOP-IT FES

by neuroConn Technologies

all-in-one solution for highly synchronized transcranial, peripheral and paired-associative closed-loop experiments 

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Closed-Loop application
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Closed-Loop - Live
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LOOP-IT - variable and customizable
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LOOP-IT_Phase_Webpage
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Loop_IT_TIS_Webpage
LOOP-IT_FES_Webpage
LOOP-IT_FES_Webpage

Features

Galvanically ilsolated modules with different functionality:
  • EEG / ECG / EMG biosignal acquisition (up to 1 ksps)

  • features of the tES current source:
    • tDCS / tACS / tRNS waveforms
    • low 1/f noise,­ < 5 mA peak-to-peak, < 5 kHz bandwidth

  • features of the NMES / FES current source:
    • constant current source for generating short, steep current pulses or pulse trains, e. g. for experiments with charge-balanced symmetric or asymmetric currents
      • any sort of AC (or DC) current waveform possible (software-defined)
      • innovation: max. 200 mApp (up to 70 V), rise time < 2 μs
    • up to 300 kHz (3 dB)
    • isolated voltage output, proportional to the output current for monitoring purposes

  • multichannel digital I/O interface (e. g. TMS, event-related potentials)

  • additional sensor interfaces for non-electrical biosignals (e. g. movement, breathing, blood flow, temperature)



Real-time system for physiological oscillation phase-dependent stimulation:

We provide a system enabling state-dependent and closed-loop controlled experiments in a stable time regimen with 1 - 3 ms turn-around time:

  • data acquisition of ExG (EEG, ECG, EMG), 3-axis acceleration 24 bit / 1 kHz

  • data analysis of amplitude, frequency, latency, phase  

  • modulation and control of the actuators tES / NMES / TMS



Direct access to hardware parameters via supplied library (Python)
Medical-grade hardware design
Standard interface and compact design
Integratable into BRAINSIGHT TMS  and ElevateTMS 

Applications

Applications of combined transcranial and peripheral Stimulation 
  • synchronized transcranial electrical and peripheral neuromuscular stimulation 
  • paired associative stimulation 

Applications in research in high-frequency electrical stimulation of the brain

Applications in research in high-frequency peripheral stimulation of the nervous systems
Conventional applications on TMS
  • Collecting EMG for MEP investigations during TMS for read out on M1
  • Collecting ECG for HR investigations during TMS for read out on DLPFC
  • Collecting EEG for TEPP investigations during TMS for read out on the whole brain

EEG & NIBS (8x EEG, 1x DIO)
  • towards personalised therapeutic brain-state dependent therapies in rehabilitation and psychiatry 

NIBS (2x tES)
  • Temporal interference stimulation for enabling targeted structures deep inside the brain by steering the electric fields of maximum amplitude modulation

NIBS & NMES (1x tES, 1x NMES)
  • Phase-dependent modulation of human corticospinal plasticity by associative pairing of transcranial and neuromuscular stimulation (tES & NMES)

product information for download

Product data sheet LOOP-IT

Portfolio for research incl. LOOP-IT

Temporal Interference Stimulation

LOOP-IT: sets new standards in neuroscie...

Poster

Real-time system for physiological oscillation phase-dependent stimulation

Poster

Current sources modules for non-invasive modulation of electro­physiology

Accessories

We offer a wide range of accessories for EEG acquisition and tES application, including electrodes of various dimensions and shapes, cables, caps and conduction pastes. Products can be ordered individually or in a set. We will also be happy to advise you which electrodes are best suited for your project.

For EEG acquisition
For tES application

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Our highly experienced engineers are available to discuss your research or lab requirements for closed-loop, neurostimulation and multimodal neuromodulation solutions.

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